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  • Q&A with Australian Health Practitioners

    Is using low dose naltrexone recommended for someone with Ulcerative Colitis?

    Hi I have been reading up about low dose naltrexone for people who UC or Crohns and have heard some good responses about. I would like to know if any one has heard about the success rate of using LDN for Sever case of Pan Ulcerative Colitis.
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    Dr van Langenberg is a consultant gastroenterologist in private practice in Melbourne's Eastern suburbs and has public hospital appointments as Director of IBD, Eastern Health … View Profile

    There is some limited evidence and scientific theory that suggests low dose naltrexone (or LDN) may be beneficial in some cases. My practice is to give it to patients who are interested in trying experimental treatments but only if standard therapies on their own have not been helpful.

    The success rate is unknown as there are no good quality trials as yet. I would recommend you try it only if you continue your usual medications for ulcerative colitis and see it as an additional treatment option.

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    Hi Dr Daniel van Langenberg

    thank you replying to my post I am welling to try anything these days my meds somedays I am not sure if working or not they seem to work ie my motions are forming but I can still go up to 5-10 times a day or have loose stools so I am welling to try anything right now such as  low dose naltrexone (or LDN) I am guessing that this will have to be prescribed to me by my GP or my Gastroenterologist? 

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    HealthShare Member

    Well could you get on the grapevine and maybe pursuade a university/medical institute to jump on this issue.

    Maybe conduct a double-blind study into  the effectiveness of naltrexone in controlling ulcerative colitis.

    Better still, in order to avoid transferring skepticism or enthusiasm to the test subjects run a TRIPLE-blind trial.

    All 30,000 Australians with UC would probably  sign up voluntarily for the test study.
    Just don't mention the drug naltrexone by name or the results will be skewed by bias.

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