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  • Q&A with Australian Health Practitioners

    What are high grade abnormalities of precancerous cells?

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    Prof Jonathan Carter

    Gynaecological Oncologist

    Professor, Department of Obstetrics and Gynaecology, The University of Sydney Head Sydney Gynaecologic Oncology Group, Royal Prince Alfred Hospital Head Gynaecology Services, Sydney South West … View Profile

    Precancer of the cervix is graded, grades one, two and three, and high grade abnormalities are classified as grades two and grade three. The term CIN, standing for Cervical Intraepithelial Neoplasia, also known as dysplasia. Basically, they're normal cells on the skin of the cervix that if left untreated, may, in the majority of cases, turn into cancer. Which may take some 7 to 10 years to do so. So high grade cervical precancer is also known as CIN2 or CIN3, and that's the rationale for treating high grade precancers to stop women developing cervical cancer. This, as I said, takes quite a number of years to occur. Commonly these days, and particularly in young women, CIN2 is not treated, as we know that some 50% to 60%of patients who have this CIN2 lesions resolve spontaneously.

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    If I don't have the hpv virus but still have a possible high grade lesion will I still need treatment ?  Or will it go away by itself? 

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