My wife has been diagnosed with depression for over 20 years but in the last 2 years it has become worse and her psychiatrist diagnosed her with Treatment Resistant Depression. She had a total of three inpatient admissions for this last year and, apart from taking antidepressants, underwent TMS and, later, ECT but with no real improvement in her condition. She has recently weaned herself off all her antidepressants but is now suffering a considerable relapse of her symptoms. Her GP wants her to go back on another antidepressant but she does not want to get side effects.
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