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  • Q&A with Australian Health Practitioners

    Is HRT safe for women who have history of severe endometriosis?

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    Endometriosis Menopause Women's Health
    Two weeks ago I had my last remaining ovary removed.

    It was a long and difficult operation as the endometriosis was severe.

    I had severe adhesions to bladder, bowel, vaginal wall, urethera tube and ovary etc.

    My concern is if HRT will be safe to take with my long history of endo (I had my other ovary and uterus previously removed because of endo and ovarian cycsts).

    So far I have had no systems, hot flushes or noticeable changes etc. I am 41.
    • 1 answer
    • Dr Joseph Jabbour
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    Dr Joseph Jabbour

    Gynaecologist, Gynaecologist - Infertility (IVF) Specialist, Obstetrician

    Dr Joseph Jabbour is a specialist Obstetrician & Gynaecologist and Fertility Specialist with Monash IVF situated in Sunnybank (Brisbane Southside). Dr Jabbour has had the … View Profile

    Firstly I hope you are recovering well from your surgery.

    The recurrence of endometriosis with low dose HRT is very low- around 3%. 

    Having had your uterus removed, you would only require oestrogen therapy. 

    The concern here is not the symptoms of menopause but the lack of hormones in a young woman below the age of 50. Oestrogen is very important in a woman of your age for the following reasons:

    1-Bone health: reduces the risk of osteoporosis and bone fractures

    2-Cardioprotective: reduction in risk of Ischemic Heart Disease and Stroke

    3-Reduction of risk of dementia and cognitive decline

    4-Good for sexual well being. 

    I would recommend a discussion with your gynaecologist in regards to the risks and benefits of being on Hormone replacement therapy at the age of 41. Definitely the benefits far outweigh the risks in your case.

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