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  • Q&A with Australian Health Practitioners

    Is ankylosing spondylitis genetic?

    If so, are there any tests I can take to pre determine if I will develop the condition?
  • Find a professional to answer your question

  • Helen Potter

    Physiotherapist

    As a Specialist Musculoskeletal Physiotherapist, with extensive experience and highly advanced qualifications, as well as excellent communication skills, I can help you to: Become informed … View Profile

    Hi
    About 95% of people with Ankylosing Spondylitis share a blood factor called HLA B27 that is tested by a blood test.

    Not everyone with this factor actually has symptoms of Ankylosing Spondylitis.

    So AS has a family link but is not as predictable as a true genetic disorder.

    Treatment has advanced considerably in the past decade so there are now much more effective medication treatments available to control symptoms. Combined with a regular exercise program and specific intermittent physiotherapy treatment will help too.

    Helen Potter FACP
    Specialist Physiotherapist
    In Touch Physiotherapy Subiaco

  • Dr Ryan Hislop

    Chiropractor

    Ryan Hislop is the Clinical Director at the Mudgee Chiropractic Health and Wellness Centre. As an experienced and evidence-based diagnostician, Ryan works largely by medical … View Profile

    It is not well understood, however almost all patients are positive for the HLA-B27 antigen. It has a moderately strong tendency to be familial and has been ascribed to a dominant gene with about 70% present in males and about 10% in females.

    Persons poisoned with cryolite and those living in areas where there is a very high concentration of fluride in the local water may develop bone changes clinically indistinguishable from ankylosing spondylitis.

  • Helen Potter

    Physiotherapist

    As a Specialist Musculoskeletal Physiotherapist, with extensive experience and highly advanced qualifications, as well as excellent communication skills, I can help you to: Become informed … View Profile

    Hi
    I suspect cryolit poisoning would be a very rare condition as Cryolite is is only found at Pikes Peak, Colorado; Mont Saint-Hilaire, Quebec; and at Miass, Russia and in small quantities in Brazil, the Czech Republic, Namibia, Norway, Ukraine!

    It will be far better for you to see a doctor for a blood test or a rheumatologist for a full assessment for an accurate diagnosis rather than worry about wha your problem might or might not be. There are so many possibilities.

    Even if you have HLA B27 you may NEVER get ankylosing Spondylitis.
    Helen Potter

  • Dr Ryan Hislop

    Chiropractor

    Ryan Hislop is the Clinical Director at the Mudgee Chiropractic Health and Wellness Centre. As an experienced and evidence-based diagnostician, Ryan works largely by medical … View Profile

    I agree with Helen. Nothing replaces the appropriate testing and examination.

    Yours sincerely,
    Ryan

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