Endocrinologist
Radioactive iodine (RAI) therapy has been used safely and effectively to treat hyperthyroidism for over 70 years and has an excellent safety record. The treatment works because the thyroid gland uniquely absorbs iodine; the radioactive form selectively destroys overactive thyroid tissue. It is given as a single capsule or liquid taken by mouth. Extensive long-term data has not demonstrated increased rates of cancer or other serious adverse effects in adults. The main consideration is that RAI frequently results in the thyroid becoming underactive (hypothyroidism) over subsequent months to years, which then requires lifelong thyroid hormone replacement. RAI is generally not used during pregnancy or in women planning pregnancy in the near term, in which case alternatives such as medication or surgery would be discussed.
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